comparison of higher-order aberrations after personalized treatment versus personalized treatment advanced photorefractive keratectomy for myopia and myopic astigmatism

purpose: the aim of this study was to compare higher-order aberrations between personalized treatment (pt) versus personalized treatment advanced (pta) photorefractive keratectomy (prk) for myopia and myopic astigmatism. methods: in this clinical trial, 80 eyes of 40 patients who met inclusion criteria were enrolled. they underwent prk using pt or pta algorithm randomly. higher-order aberrations were measured and compared between the study groups pre-operatively and at months 3 and 6 postoperatively. results: the two study groups were comparable in terms of preoperative higher-order aberrations. compared to the preoperative values, higher-order aberrations were significantly increased in the pt group (p<0.001), but decreased in the pta group (p<0.001). spherical aberration exhibited a significant increase postoperatively in the pt group (p<0.001) but remained unchanged in the pta group (p=0.57). conclusion: prk using pt algorithm resulted in an increase higher-order aberrations. pta algorithm provided better results in terms of postoperative higher-order aberrations and could treat pre-existing higher-order aberrations.